Shifa Pharmed Industrial Group was founded in 1996 with the aim of manufacturing 300 tons different types of antibiotics including Erythromycin Base, which is the first antibiotic manufactured by biotechnological methods using fermentation in Iran. Erythromycin Base, as a parent molecule, is used for production of Macrolide Antibiotics group including Erythromycin Ethyl Succinate, Azithromycin, Clarithromycin and Roxithromycin. In 1999, simultaneous with the basic changes in the company structure in order to finance the projects partly and to start the practical production of the antibiotics, the design and construction of Erythromycin Ethyl Succinate production line from Erythromycin Base was started with the manufacturing capacity of 100 tons per year and has been in operation since 2000. This line has been improved continuously through application of the latest technologies to produce a world-class product. At the next stage, the company operated a new line to produce Azithromycin out of Erythromycin Base at 20 tons capacity in 2006 and at the same time started to study and research into producing active ingredients of Clarithromycin which then was successfully operationalized. Developing the macrolide products portfolio is still the top priority of Shifa Pharmed Industrial Group. Some of these products include Azithromycin Test mask that was established in 2012.
Geographical Location and Land Area:
The factory was built in an area measuring 230,000 square meters in Pharmaceutical Industrial Park of Barakat, Kordan village, Alborz province.
The project of producing raw materials for Penicillin G:
The latest achievement of Shifa Pharmed Industrial Group is the great project of penicillin G mass production. Penicillin G is the initial parent molecule of β-lactam antibiotics synthesis. These β-lactam antibiotics are the most commonly used group of antibiotics in the world. This strategic project can potentially manufacture 1300 tons of raw materials for Penicillin G which in fact meets the country’s demand and hence the county would not have to import this precious material.
Key features of the project:
- Manufacturing 1300 tons of raw materials for Penicillin G (pen.g) from living cells in Shifa Pharmed Company per year;
- Providing biotechnology equipment and implementing Penicillin G project on an industrial scale;
- Deploying fermentation method on a large scale for the first time in the region, ranging from China to Europe;
- Developing and localizing of technical-biotechnology knowledge of building fermenters (internal capacity of 140 thousand liters) and building industrial bioreactors for the first time in Iran;
- Developing agriculture and food industry through Penicillin G Cake as feed and producing glucose, sucrose and corn oil;
- As much as 30 million dollars investment
As one of the manufacturers of raw materials for various essential antibiotics, Shifa Pharmed Industrial Group has employed 750 experts that directly and indirectly work for it.
Certificates and appreciation letters:
Shifa Pharmed Industrial Group was set up in compliance with all international pharmaceutical and global managerial principles and standards. Shifa Pharmed Industrial Group has obtained some standards including GLP certificate from MOH Drug & Food Control Laboratories department in 2006, ISO 9001-2000 in management, design, and Halal certificate from special body in the organization of Islamic conference (ICRIC).